Pump calibration using Alker software
Pump calibration is necessary to translate flow rate units of milliliters per minute to revolutions per minute (RPM) signals used by the controller box to […]
Overcoming viscosity variability during alkaline mixing
A well-known problem with the lysis operation is the real-time increase in viscosity when the NaOH-SDS buffer mixes with resuspended bacterial cells. This results in […]
gmp production
Crosser TFF
• Personalized manufacturing ready
• High dynamic range: 2mL to 500L UF/DF
• Small factory footprint: 45 cm2
• Pressure control: ±0.05 psi, latency: 2 min
• GMP ready, clinically proven
• 100% single-use flow path
atmp process development
Alker 3L
The only off-the-shelf bioprocessing solution for alkaline lysis of plasmid DNA at 0.1 – 3L fermentation scales. Validated for pDNA process development in fast-paced clinical manufacturing projects. Web-based software provides flexible automation, PID-controlled process parameters, and minimal operator training. Fully computer-controlled processes at small scales facilitate future scale-up studies.
